40-80 mg daily. Max single dose: 160 mg. Higher doses, split into bd dosing. Elderly Initially, 40 mg bd as morning & evening doses.
Administration
Should be taken with food: Take immediately before meals.
Contraindications
IDDM, diabetic ketoacidosis, diabetic coma & pre-coma, hyperosmolar non-ketotic coma, after severe burns, trauma or during infections, diabetics undergoing surgery. Pregnancy & lactation.
Special Precautions
Severe diarrhoea, severe gastroparesis, intestinal obstruction, prolonged vomiting, thyroid dysfunction.
Adverse Reactions
GI disturbances, metallic taste, increased appetite, wt gain, rash, pruritus, photosensitivity.